It became known that kills malarial mosquitoes

Стало известно, что убивает малярийных москитов

The fungus has reduced populations of insecticide-resistant mosquitoes is critical.

The new method operates quickly and reduces the insect population to such values at which no further reproduction impossible, wrote the Chronicle.info with reference to the Telegraph.

Scientists at the University of Maryland, College Park and Research Institute in Bobo-Dioulasso (Burkina Faso) tested a genetically modified fungus Metarhizium pingshaense. The results were published in the journal Science.

According to the world health organization (who) in 2017 malaria sick 219 million people in 87 countries, with the estimated number of deaths from malaria in that year reached 435 thousand. Scientists are trying to fight infection by lowering the number of mosquitoes, but insects adapt and become resistant to insecticides. Therefore, we are constantly searching for new methods of struggle. Recent tests have shown that the rate of destruction of the carriers of the disease transgenic fungus is higher than their rate of reproduction, which gives unprecedented results.

“No method of malaria control is not as far advanced field trials. This article sets a precedent and marks a big step forward for this and other transgenic methods,” said lead author Brian Lovett (Brian Lovett).

The fungus Metarhizium pingshaense has a pathogen which is slowly killing insects in the wild. It was used to combat agricultural pests. Researchers chose a strain of the fungus, typical for mosquitoes, and combined it with a toxin that kills these insects is much faster.

Toxin known as “hybrid” (Hybrid) experts have received from the poison mygalomorph spiders Hadronyche versuta. Its use is endorsed protection Agency United States environmental protection Agency (EPA). To change the DNA of the fungus, the scientists used the bacteria. They not only changed the secreted toxin, but also reconfigure the time of its release. Typically, the fungus produces to protect it when he “feels” is in a hostile environment, but its a modified version of the mosquito recognizes and penetrates the cuticle, and then to release the toxin. The fungus is not dangerous to other insects, which was confirmed by additional tests.

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In order to test the effectiveness of transgenic Metarhizium pingshaense, the authors conducted an experiment. In Burkina Faso, they built a shielded structure called MosquitoSphere. It was preserved in conditions close to real, which allowed insects to maintain the population size. In each of the three cells, the researchers launched a thousand adult males and 500 females. Inside hung black cotton sheets coated with sesame oil. In the first chamber oil mixed with a modified mushroom, the second with a wild mushroom version, the third oil is left unchanged. For the life of the colonies the authors observed for 45 days. After that, they summed up: in the third chamber remained 1396 mosquitoes, and secondly — 455, first — 13.

Brian Lovett explained that the number of individuals that remained in the first chamber, is not enough to restore the colony. Genetically modified fungus have acted the same way as in normal mosquitoes and are resistant to insecticides. The next step will be testing in a local village.

In one of the most dangerous regions of the planet discovered microorganisms

Previously, biologists from the University of Florida have identified a protein receptor in mosquitoes that responds to the presence in the air of lactic acid is a characteristic marker of human sweat.

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